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Microbiome Research

The Oklahoma Center for Microbiome Research broadly addresses key principles and questions concerning microbiome structure and function as the underpinnings of One Health. This research center supports and promotes research excellence while facilitating early-stage investigators’ progress towards independence. A key to achieving the objectives and long-term goals is the coordination of research activities, career development, and mentoring. The primary focus of the OCMR is to promote the success of Research Project Leaders in achieving milestones. Research capacity is enhanced by an Anaerobic Microbiology Research Core that provides customized culturomics services, including a novel approach for sequence-guided, targeted culture isolation by using reverse genomics to prepare tagged-nanobodies to surface proteins, paired with anaerobic cell sorting to isolate single living cells.

 

Anaerobic Microbiology Core Facility

The Oklahoma Center for Microbiome Research aims to accelerate cutting-edge multidisciplinary research on microbiome structure and function and facilitate the transition of five new investigators to R01 funding. An Anaerobic Microbiology Research Core is being created so we can reach this overall goal. The Anaerobic Core will provide anaerobic microbiology expertise, instrumentation, and training in anaerobic culturomics, as well as support all five research projects. It is the first entity in Oklahoma to provide customized culturomics services. To learn more about the Anaerobic Microbiology Research Core facility, click here.

 

 

 

Research Projects and MentorsLearn about our five research projects and the research project leaders, as well as the mentors supporting them.

Research Projects

The Oklahoma Center for Microbiome Research consists of five research projects being led by amazing Research Project Leaders.

  • Project 1: Oral pathogen-triggered progression of oral squamous cell carcinoma.
  • Project 2: Engineering host-determinants of novel gut microviruses.
  • Project 3: Microbiome response to dietary carotenoids.
  • Project 4: Characterizing Pathogen-Mediated Production of Secondary Metabolites in the Human Aerodigestive Tract Microbiome.
  • Project 5: The adolescent microbiome-gut-brain axis as a potential target in opioid abuse disorders.

Mentors

Supporting each Research Project Leader is two mentors. Learn more about Oklahoma Center for Microbiome Research's supportive mentors.

  • Mostafa Elshahed
  • Clinton Jones
  • Gerwald Koehler
  • Lijun Xia
  • Stephen Clarke
  • Janeen Johnson-Salak
  • Paul Lawson
  • Kyle Simmons

 

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