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Arts and Sciences

Chemistry

Publications

Preprints

29.

Tarosha Salpadoru, Sharmily S. Khanam, V. Borin, Maha Achour, Denise Oh, Mert Kanik, Prasadi C. Gallage, Anna Khanov, Mackenzie Hull, Spencer P. Pitre, Pratul K. Agarwal, Michael J. Franklin and Marianna A. Patrauchan*. A Novel Non-Catalytic Function of PA2803-Encoded PcrP Contributes to Polymyxin B Resistance in P. Aeruginosa and Redefines the Functional Role of the PA2803 Subfamily.bioRxiv2025, DOI: . Under Review.

Publications at OSU

28.

Tarannum Tasnim, Negin Shafiei, Katelyn J. Laminack, Bailey S. Robertson, Nash E. Nevels, Christopher J. Fennell and Spencer P. Pitre*. A Dual Catalytic Approach for the Halogen-Bonding-Mediated Reductive Cleavage of α-Bromodifluoroesters and Amides. The Journal of Organic Chemistry 2025, 90, 863–871.

Finkelstein TOC Graphic

27.

K. A. Viraj Miyuranga, Kaitlin E. Ashcraft and Spencer P. Pitre*. A Modern Approach to Intermittent Illumination for the Characterization of Chain-Propagation in Photoredox Catalysis. Tetrahedron Chem 2024, 12, 100110.

Tetrahedron Chem Graphical Abstract

Part of the Photocatalysis in Organic Synthesis Special Issue.

26.

John Hayford G. Teye-Kau and Spencer P. Pitre*. Dichloromethane.Encyclopedia of Reagents for Organic Synthesis. 2025, DOI: 10.1002/047084289X.rn02644.

25.

Adrián Gómez-Suárez*, Spencer P. Pitre* and Chen Zhu*. A Radical Revolution in the 21st Century. ChemCatChem2024, 16, e202401079. [Editorial]

24.

Prasadi C. Gallage, Mary G. McKee and Spencer P. Pitre*. 1,4-Dihydropyridine Anions as Potent Single-Electron Photoreductants. Organic Letters 2024, 26, 1975–1979.

TOC Graphic

23.

John Hayford G. Teye-Kau, Mayokun J. Ayodele and Spencer P. Pitre*. Vitamin B12-Photocatalyzed Cyclopropanation of Electron-Deficient Alkenes using Dischloromethane as a Methylene Source. Angewandte Chemie International Edition2024, 63, e202316064.

Updated Graphical Abstract

Featured by OSU News and highlighted by OPR&Dand Synfacts.

22.

Prasadi C. Gallage and Spencer P. Pitre*. Direct photolysis of 4-tert-alkyl-1,4-dihydropyridines under blue-light irradiation for the generation of tertiary alkyl radicals. Green Chemistry2022, 24, 6845–6848.

TOC

21.

Tarannum Tasnim, Mayokun J. Ayodele and Spencer P. Pitre*. Recent Advances in Employing Catalytic Donors and Acceptors in Electron Donor-Acceptor Complex Photochemistry. Journal of Organic Chemistry2022, 87, 10555–10563.

Synopsis TOC graphic

20.

Spencer P. Pitre. Radical coupling decreases synthetic burden. Science2022, 375, 1234. [Invited Perspective]

19.

Tarannum Tasnim, Calvin Ryan, Miranda L. Christensen, Christopher J. Fennell and Spencer P. Pitre*. Radical Perfluoroalkylation Enabled by a Catalytically Generated Halogen Bonding Complex and Visible Light Irradiation. Organic Letters 2022, 24, 446–450.

Perfluoroalkylation TOC

Org Lett Cover

18.

Spencer P. Pitre* and Larry E. Overman*. Strategic Use of Visible-Light Photoredox Catalysis in Natural Product Synthesis. Chemical Reviews 2022, 122, 1717–1751.

TOC Chem Rev

Part of the Photochemical Catalytic Processes Special Issue.

Publications Prior to OSU

17.Pitre, S. P.; Allred, T. K.; Overman, L. E. Lewis Acid Activation of Fragment-Coupling Reactions of Tertiary Carbon Radicals Promoted by Visible Light Irradiation of EDA Complexes. Organic Letters 2021, 23, 1103–1106.
16.Pitre, S. P.; Muuronen, M.; Fishman, D. A.; Overman, L. E. Tertiary Alcohols as Radical Precursors for the Introduction of Tertiary Substituents into Heteroarenes. ACS Catalysis 2019, 9, 3413–3418.
15.Pitre, S. P.; Weires, N. A.; Overman, L. E. Forging C(sp3)–C(sp3) Bonds with Carbon-Centered Radicals in the Synthesis of Complex Molecules. Journal of the American Chemical Society 2019,141, 2800–2813.
14.McCallum, T.; Pitre, S. P.; Morin, M.; Scaiano, J. C.; Barriault, L. The photochemical alkylation and reduction of heteroarenes. Chemical Science2017, 8, 7412–7418.
13.Pitre, S. P.; Scaiano, J. C.; Yoon, T. P. Photocatalytic Indole Diels–Alder Cycloadditions Mediated by Heterogeneous Platinum-Modified Titanium Dioxide. ACS Catalysis2017, 7, 6440–6444.
12.Pitre, S. P.; Yoon, T. P.; Scaiano, J. C. Titanium Dioxide Visible Light Photocatalysis: Surface Association Enables Photocatalysis with Visible Light Irradiation. Chemical Communications2017, 53, 4335–4338.
11.Garcia, A. M., de Alwis Weerasekera, H.; Pitre, S. P.; McNeill, B.; Lissi, E.; Edwards, A. M.; Alarcon, E. M. Photodynamic performance of zinc phthalocyanine in HeLa cells: A comparison between DPCC liposomes and BSA as delivery systems. Journal of Photochemistry and Photobiology B: Biology2016, 163, 385–390.
10.Pitre, S. P.; McTiernan, C. D.; Scaiano, J. C. Library of Cationic Organic Dyes for Visible-Light-Driven Photoredox Transformations. ACS Omega2016, 1, 66–76.
9.Pitre, S. P.; McTiernan, C. D.; Scaiano, J. C. Understanding the Kinetics and Spectroscopy of Photoredox Catalysis and Transition-Metal Free Alternatives. Accounts of Chemical Research. 2016, 49, 1320–1330.
8.Pitre, S. P.; McTiernan, C. D.; Vine, W.; DiPucchio, R.; Grenier, M.; Scaiano, J. C. Visible-Light Actinometry and Intermittent Illumination as Convenient Tools to Study Ru(bpy)3Cl2 Mediated Photoredox Transformations. Scientific Reports2015, 5, 16397.
7.Favrelle, A.; Gouhier, G.; Guillen, F.; Martin, C.; Mofaddel, N.; Petit, S.; Mundy, K. M.; Pitre, S. P.; Wagner, B. D. Structure-Binding Effects: Comparative Binding of 2-Anilino-6-naphthalenesulfonate by a Series of Alkyl- and Hydroxyalkyl-Substituted β-Cyclodextrins. Journal of Physical Chemistry B2015, 119, 12921–12930.
6.McTiernan, C. D., Pitre, S. P., Scaiano, J. C. Photocatalytic Dehalogenation of Vicinal Dibromo Compounds Utilizing Sexithiophene and Visible-Light Irradiation. ACS Catalysis2014, 4, 4034–4039.
5.McTiernan, C. D., Pitre, S. P., Ismail, H., Scaiano, J. C. Heterogeneous Light-Mediated Reductive Dehalogenations and Cyclizations Utilizing Platinum Nanoparticles on Titania (Pt@TiO2).Advanced Synthesis & Catalysis2014, 356, 2819–2824.
4.Pitre, S. P., McTiernan, C. D., Ismaili, H., Scaiano, J. C. Metal-Free Photocatalytic Radical Trifluoromethylation Utilizing Methylene Blue and Visible Light Irradiation. ACS Catalysis2014, 4, 2530–2535.
3.Pitre, S. P., McTiernan, C. D., Ismaili, H., Scaiano, J. C. Mechanistic Insights and Kinetic Analysis for the Oxidative Hydroxylation of Arylboronic Acids by Visible Light Photoredox Catalysis: A Metal-Free Alternative. Journal of the American Chemical Society2013135, 13286–13289.
2.Carter Ramirez, D. M., Pitre, S. P., Kim, Y. A., Bittman, R., Johnston, L. J. Photouncaging of Ceramides Promotes Reorganization of Liquid-Ordered Domains in Supported Lipid Bilayers. Langmuir2013, 29, 3380–3387.
1.Ismaili, H., Pitre, S. P., Scaiano, J. C. Active participation of amine derived radicals in photoredox catalysis as exemplified by a reductive cyclization. Catalysis Science & Technology2013, 3, 935–937.