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Dr. Berlin

Dr. K. Darrell Berlin

Emeritus Regents Professor

 413 Physical Sciences I
Retired: Fall 2021 but still researches at OSU.



  • B.A., 1955, North Central College
  • Ph.D., 1958, University of Illinois

Postdoctoral Appointments:

  • WADC Postdoctoral Fellow, 1958-60, University of Florida

Dr. Berlin retired from teaching duties in the Fall of 2021. 


 Research Interests:

  • Organic synthetic methods
  • Medicinal chemistry
  • Heteroarotinoids as anti-cancer agents
  • Heterocycles
  • Organophosphorus chemistry
  • NMR analysis of dynamic systems


Our research efforts are focused upon synthesis.  The research involves the development of agents to treat a variety of cancers. The heteroarotinoid 1 (X = Y = S; Z = NO2) below has successfully passed all pre-clinical screening for the potential treatment of kidney and ovarian cancer.  Plans are to begin PHASE 0 and PHASE 1 clinical trials in 2018 involving humans. Research is continuing with the objective to synthesize modified versions of the clinical agent.


berlin created molecule

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